Tuesday, June 5, 2018

The beat goes on...

The US Federal government has moved to control five new synthetic cannabinoids as Schedule I controlled  substances.

Synthetic cannabinoid herbal incense
Image by Kevin G. Shanks (2017)

These newer alphabet soup synthetic cannabinoids include:

4-CN-CUMYL-BUTINACA
1-(4-cyanobutyl)-N-(1-methyl-1-phenylethyl)-1H-indazole-3-carboxamide

5F-AB-PINACA
N-[(1S)-1-(aminocarbonyl)-2-methylpropyl]-1-(5-fluoropentyl)-1H-indazole-3-carboxamide

4-CN-CUMYL-BUT7AICA
1-(4-cyanobutyl)-N-(1-methyl-1-phenylethyl)-1H-pyrrolo[2,3-b]pyridine-3-carboxamide

MMB-CHMICA
Methyl(1-(cyclohexylmethyl)-1H-indole-3-carbonyl)-L-valinate

NM2201
Napthalen-1-yl 1-(5-fluoropentyl)-1H-indole-3-carboxylate



Chemical Structures of Newly Controlled Cannabinoids
Drawn by Kevin G. Shanks (2018)

With the inclusion of these five substances, the Federal government has now scheduled 38 synthetic cannabinoids since 2011. In case you want to learn more about synthetic cannabinoids, I wrote a 2.5 minute primer on them quite a while ago. It's a quick read and is still more than applicable -  you can find it here.

Also, there are many posts about these substances on this blog. Please read some of them as these are substances of extreme toxicological importance. These substances are cheap. They are used for convenience and to evade drug tests for THC. They are easy to get ahold of. Yet, they are complete pharmacological and toxicological unknowns. As I usually say, when people consume products containing synthetic cannabinoids, they are ingesting substances of unknown identification with unknown pharmacological and toxicology properties in unknown dosages in unknown combinations. It's a recipe for disaster.


And the beat goes on...

Stay safe.


References

United States DEA (2018) Notice of Intent: Schedules of Controlled Substances: Temporary Placement of NM2201, 5F-AB-PINACA, 4-CN-CUMYL-BUTINACA, MMB-CHMICA, and 5F-CUMYL-P7AICA Into Schedule I.
Federal Register, Volume 83, Number 103
https://www.deadiversion.usdoj.gov/fed_regs/rules/2018/fr0530.htm

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