Alphabet Soup Or The Newer Synthetic Cannabinoids

It seems as if the early compounds were the easiest to identify by name as they were series compounds (i.e. JWH-xxx or AM-xxxx).  Now we have what I like to call the alphabet soup compounds…

AB-PINACA, 5F-AB-PINACA, AB-FUBINACA
ADB-PINACA, 5F-ADB-PINACA, ADB-FUBINACA
FUB-PB-22 and FDU-PB-22
THJ and 5F-THJ
………
Here are chemical structures of these compounds:
Now it seems as if we are mixing and matching various structural groups at an increasing rate…indoles, indazoles, hydroxyquinolines, aminoquinolines, hydroxynaphthoyls, isopropyl groups, tert-butyl groups, halogens, alkyl chains…a chemist’s dream.
Also, a nightmare…keep in mind that no one knows what the actual pharmacological or toxicological properties of these drugs are. Do these substances act on only cannabinoid receptor? What downstream effects occur? What are short term and long term effects of use? How are these substances metabolized? What are the prominent metabolites? Do the metabolites have pharmacological activity?
The CDC released case studies through Morbidity and Mortality Weekly Report (MMWR) in February 2013 and November 2013 regarding significant injury and illnesses resulting from use of some synthetic cannabinoid-containing products. The February information included the detection of the cyclopropylindole cannabinoid, XLR-11, and associated it with acute kidney injury in a series of patients in various locations. The November information included the detection of ADB-PINACA in the blood of five patients admitted to the hospital in Georgia.
We’ll see if any of these compounds become prevalent in herbal blends and products. Unfortunately, the truth is that we won’t know about their true prevalence until we see their adverse effects, which may be as presentations to a hospital's emergency department or analyses during postmortem toxicology.  And then, it’s too late.
Be safe out there.

7 comments:

  1. Ambien is a sedative used in the treatment of sleep problems, insomnia or sleeplessness. It works on the chemicals in the brain which may be imbalanced in people suffering through these situations due to stress and overworking. There are a few important facts enlisted below that you might know before you buy Ambien online
    buy hydrocodone online at resonable price without prescription.

    buy adderall online from our online phamracy. we are the top online medicines provider in all over USA.

    buy codeine online from our online phamracy. we are the top online medicines provider in all over USA.

    ReplyDelete
  2. Wow what an amazing post, such a great blog, i will come back and read more
    Order fluvet 10ml online
    Buying steroids-Rexobol 50x 50mg online
    magic mushroom shrooms for sale online,
    hydrogel buttock injection 1000cc online
    Where to buy heroin 99% purity online
    For more information and quick updates, wickr: drubybay1010, Whatsapp: +14013083901 for more information

    ReplyDelete
  3. We are supplier of high Quality research chemicals ,Pills & venom at good and affordable prices.

    Contact Us:
    Delta Bio-research Chemicals
    https://deltabioresearchchemicals.com/
    skype: live:deltabioresearchchemicals
    Whatsapp:+1(619) 356-8501
    Email:support@deltabioresearchchemicals.com

    Buy Etizolam Powder Online
    research chemicals
    buy ketamine online
    buy xanax powder online
    buy bk-mdma online

    ReplyDelete
  4. We are one of international premium providers of 25 I-NBOMe , 2-FMA , 4-MEC , 5-fur-144 , 5-mapb for sell , A-php crystal , Actavis cough syrup 16 oz ,Actavis cough syrup 32 oz , AK-B48 , Amphetamine Speed paste , Buy A-pvp , AM-2201 , Ecstasy Party Pills , Dibutylone Crystal , global Temazepam , High quality Heroin for sell , mdpv crystal , Methamphetamine Ice crystal Crystal , Liquid Ecstasy , mdma crystal , Methoxetamine , Pentedrone , *Pang Baduy*-22 , Methylone Crystals … Discrete Overnight Shipping within usa to Australia, Canada, UK, Germany, Sweden ,spain, New Zealand, Scandinavia, Finland, Iceland, Latvia, Estonia etc .We are proud of offer high quality Research chemicals product, one of most reliable company on the market and get satisfied feedback from our customers.Our prices include registered air mail delivery. Delivery time 2-3 days. ..we sale both in wholesale and retail prices.Please visit us below for info

    Website: https://herbalincensekush.com


    E-mail : k2bestherbalincense@gmail.com

    Call: +1 (614) 245 5317 (usa/Canada)

    whatsapp: +1 (614) 245 5317

    Link: Buy Fentanyl online

    Link: Buy Pure Grade Heroin online

    Link: Buy Cocaine Powder online

    Link: Buy Ghb powder for sale

    ReplyDelete
  5. we offer top quality bath salts,herbal incense,research chemicals,actavis prometh,nembutal,HGH,steroids,pain pills,weight loss pills,marijuana,weed,weight gain pills and many other products.Our products are top quality,packaging and shipping is discrete.Only you and us know what is in your package.Special discounts on wholesale orders. Visit our official website to place an order now.
    Call / Text us directly via +1(925)-338-9583 for more details
    visit our website: https://shop4herbalincense.com

    ReplyDelete
  6. Hi There,
    Thank you for sharing a knowledgeable blog with us I hope that you will post many more blog with us:
    Nembutal Liquid, Pentobarbital (trade name: Nembutal) is a drug from the barbiturate class. It was widely used during the 1940s and 1950s as a sleeping pill.Discover ideas about James Bond. Purchase nembutal online from VIDA TERMINO. We have high quality nembutal for sale.
    Click here for Buy Nembutal Online

    ReplyDelete