Wednesday, October 29, 2014

Another day, another new synthetic cannabinoid...

The state of Louisiana has just banned another new synthetic cannabinoid derivative which has been associated with greater than 125 hospitalizations in the Baton Rouge vicinity since October 3, 2014 (I am not sure if these were analytically confirmed in blood/urine; I'm assuming not - I do not know any person or lab that is analyzing for this compound).

The newer synthetic cannabinoid is named MAB-CHMINACA, but is probably more widely known as ADB-CHMINACA.


ADB-CHMINACA (pictured above with other chemical structure derivatives) is a member of the now prevalent indazole carboxamide family of synthetic cannabinoids. Its chemical name is N-(1-amino-3,3-dimethyl-1-oxobutan-2-yl)-1-(cyclohexylmethyl)-1H-indazole-3-carboxamide. Chemical formula is C21H30N4O2.

The alphabet soup naming convention is defined as:

AminoDimethyloxoButaneCycloHexylMethylINdAzoleCarboxAmide

Even though it is suspected to be a synthetic cannabinoid receptor 1 and 2 agonist, the pharmacology and toxicology of this compound is unknown at this time. This compound's emergence on the designer drug market is just another part of the cat-and-mouse game that we've seen over the last several years.

"And the beat goes on, the beat goes on
Drums keep pounding a rhythm to the brain..."

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The emergency rule issued by the State of Louisiana Department of Health and Hospitals can be found here.

News reports about the ban can be found here and here.
 

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