Chemical structures of THC-carboxylic acid metabolite and PCP
Drug detection windows in urine are variable and approximate and ultimately depend on a myriad of factors including the nature of the drug consumed, the route of administration of drug, the individual's metabolism, the dosage of drug consumed, the dosage form of the drug consumed, and the hydration state of the individual.
So, here's a handy list for some routine drugs:
Analyte | Time Range |
6-acetylmorphine | 12 - 24 hours |
7-aminoclonazepam | 1 - 10 days |
Acetaminophen | 1 - 2 days |
Alprazolam and alphahydroxyalprazolam | 1 - 4 days |
Amobarbital | 1 - 5 days |
Amphetamine | 1 - 5 days |
Benzoylecgonine | 1 - 4 days |
Buprenorpine and norbuprenorphine | 1 - 10 days |
Butabarbital | 1 - 5 days |
Butalbital | 1 - 5 days |
Carisoprodol | 1 - 2 days |
Codeine | 1 - 4 days |
Ethanol | 1 - 24 hours |
Ethyl Glucuronide | 1 - 3 days |
Fentanyl and norfentanyl | 1 - 4 days |
Gabapentin | 1 - 4 days |
Hydrocodone | 1 - 4 days |
Hydromorphone | 1 - 4 days |
Lorazepam | 1 - 4 days |
MDMA | 1 - 5 days |
Meprobamate | 1 - 4 days |
Methadone and EDDP | 1 - 10 days |
Methamphetamine | 1 - 5 days |
Morphine | 1 - 4 days |
Nordiazepam | 1 - 10 days |
Oxazepam | 1 - 10 days |
Oxycodone | 1 - 4 days |
Oxymorphone | 1 - 4 days |
PCP | 1 - 8 days |
Pentobarbital | 1 - 3 days |
Phenobarbital | 1 - 30 days |
Phentermine | 1 - 4 days |
Pregabalin | 1 - 4 days |
Propoxyphene and norpropoxyphene | 1 - 5 days |
Secobarbital | 1 - 3 days |
Tapentadol | 1 - 2 days |
Temazepam | 1 - 10 days |
THC-COOH (frequent user) | 1- 30 days |
THC-COOH (occasional user) | 1 - 4 days |
Tramadol and nortramadol | 1 - 4 days |
It is important to remember that the urine matrix is a waste/excretory product. Drugs or drug metabolites detected in the urine are not exerting a pharmacological effect on the body. Also, there is no correlation between an ingested dose and the resulting urine concentration of drug/metabolite. If these are a concern, then blood analysis should be undertaken, but it should be noted that detection of drug or metabolite in the blood matrix is typically considerably shorter than the urine window of detection.
Cheers,
ForensicToxGuy
Diphenhydramine 30+ days, by LC/MS of course. LC/MS a blessing and a curse.
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